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Array_dataset_Male

ABSTRACT: DNAm Case samples using Illumina Infinium 450K

PROVIDER: EGAD00010001260 | EGA |

REPOSITORIES: EGA

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Widespread DNA hypomethylation and differential gene expression in Turner syndrome.

Trolle Christian C Nielsen Morten Muhlig MM Skakkebæk Anne A Lamy Philippe P Vang Søren S Hedegaard Jakob J Nordentoft Iver I Ørntoft Torben Falck TF Pedersen Jakob Skou JS Gravholt Claus Højbjerg CH

Scientific reports 20160930

Adults with 45,X monosomy (Turner syndrome) reflect a surviving minority since more than 99% of fetuses with 45,X monosomy die in utero. In adulthood 45,X monosomy is associated with increased morbidity and mortality, although strikingly heterogeneous with some individuals left untouched while others suffer from cardiovascular disease, autoimmune disease and infertility. The present study investigates the leukocyte DNAmethylation profile by using the 450K-Illumina Infinium assay and the leukocyt ...[more]

PMID: 27687697

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