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Dataset Information

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Institute of Human Genetics, Medical University Graz

ABSTRACT: Organisation EGAO00000000098

PROVIDER: EGAO00000000098 | EGA |

REPOSITORIES: EGA

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Publications

The analysis of cell-free DNA (cfDNA) in plasma represents a rapidly advancing field in medicine. cfDNA consists predominantly of nucleosome-protected DNA shed into the bloodstream by cells undergoing apoptosis. We performed whole-genome sequencing of plasma DNA and identified two discrete regions at transcription start sites (TSSs) where nucleosome occupancy results in different read depth coverage patterns for expressed and silent genes. By employing machine learning for gene classification, w  ...[more]

PMID: 27571261

Publication: 1/2

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