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Dataset Information

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McGill University, University of Tromso


ABSTRACT: Organisation EGAO00000000177

PROVIDER: EGAO00000000177 | EGA |

REPOSITORIES: EGA

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Publications

Peripheral blood cells inform on the presence of breast cancer: a population-based case-control study.

Dumeaux Vanessa V   Ursini-Siegel Josie J   Flatberg Arnar A   Fjosne Hans E HE   Frantzen Jan-Ole JO   Holmen Marit Muri MM   Rodegerdts Enno E   Schlichting Ellen E   Lund Eiliv E  

International journal of cancer 20140625 3


Tumor-host interactions extend beyond the local microenvironment and cancer development largely depends on the ability of malignant cells to hijack and exploit the normal physiological processes of the host. Here, we established that many genes within peripheral blood cells show differential expression when an untreated breast cancer (BC) is present, and harnessed this fact to construct a 50-gene signature that distinguish BC patients from population-based controls. Our results were derived from  ...[more]

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