Project description:Mixed-lineage leukemias represent about 3-5% of acute leukemias occurring in patients of all ages and comprise several different subtypes (biphenotypic, bilineal, and lineage switch). The optimal therapeutic approach to these cases, especially in pediatric patients, has not been defined. We used microarrays to detail the gene expression of pediatric patients with biophenotypic leukemia. Keywords: Patient sample accumulation
Project description:we adopted DIA-MS method to profile serum proteome signatures of acute asthma children and convalescent ones. As result, we identified 747 proteins were identified in 46 serum samples and detected 37 differentially expressed proteins that could clearly separate asthmatic and healthy children.