Dataset Information
University College London
Ontology highlight
ABSTRACT:
PROVIDER: EGAO00000000420 | EGA |
REPOSITORIES: EGA
Publications
Genetic variability in the regulation of gene expression in ten regions of the human brain.
Nature neuroscience 20140831 10
Germ-line genetic control of gene expression occurs via expression quantitative trait loci (eQTLs). We present a large, exon-specific eQTL data set covering ten human brain regions. We found that cis-eQTL signals (within 1 Mb of their target gene) were numerous, and many acted heterogeneously among regions and exons. Co-regulation analysis of shared eQTL signals produced well-defined modules of region-specific co-regulated genes, in contrast to standard coexpression analysis of the same samples. ...[more]
