Genomics

Dataset Information

0

National University of Singapore


ABSTRACT: Organisation EGAO00000000868

ORGANISM(S): Homo sapiens  

PROVIDER: EGAO00000000868 | EGA |

REPOSITORIES: EGA

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Publications

Characterising private and shared signatures of positive selection in 37 Asian populations.

Liu Xuanyao X   Lu Dongsheng D   Saw Woei-Yuh WY   Shaw Philip J PJ   Wangkumhang Pongsakorn P   Ngamphiw Chumpol C   Fucharoen Suthat S   Lert-Itthiporn Worachart W   Chin-Inmanu Kwanrutai K   Chau Tran Nguyen Bich TN   Anders Katie K   Kasturiratne Anuradhani A   de Silva H Janaka HJ   Katsuya Tomohiro T   Kimura Ryosuke R   Nabika Toru T   Ohkubo Takayoshi T   Tabara Yasuharu Y   Takeuchi Fumihiko F   Yamamoto Ken K   Yokota Mitsuhiro M   Mamatyusupu Dolikun D   Yang Wenjun W   Chung Yeun-Jun YJ   Jin Li L   Hoh Boon-Peng BP   Wickremasinghe Ananda R AR   Ong RickTwee-Hee RH   Khor Chiea-Chuen CC   Dunstan Sarah J SJ   Simmons Cameron C   Tongsima Sissades S   Suriyaphol Prapat P   Kato Norihiro N   Xu Shuhua S   Teo Yik-Ying YY  

European journal of human genetics : EJHG 20170118 4


The Asian Diversity Project (ADP) assembled 37 cosmopolitan and ethnic minority populations in Asia that have been densely genotyped across over half a million markers to study patterns of genetic diversity and positive natural selection. We performed population structure analyses of the ADP populations and divided these populations into four major groups based on their genographic information. By applying a highly sensitive algorithm haploPS to locate genomic signatures of positive selection, 1  ...[more]

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