The Transcriptome of PLX4032 resistance
Ontology highlight
ABSTRACT:
PROVIDER: EGAS00001000413 | EGA |
REPOSITORIES: EGA
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Project description:We have collected material from a patient who had BrafV600E mutant melanoma that was treated with PLX4032. We have germline DNA from the patient and DNA and RNA from distinct lesions before and after treatment with PLX4032. We have transcriptome sequenced these samples to obtain a snap shot of the mechanisms of resistance that are operative.
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Project description:We have collected material from a patient who had BrafV600E mutant melanoma that was
treated with PLX4032. We have germline DNA from the patient and DNA and RNA from
distinct lesions before and after treatment with PLX4032. We have transcriptome sequenced these samples to obtain a snap shot of the mechanisms of resistance that are operative.
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treated with PLX4032. We have germline DNA from the patient and DNA and RNA from
distinct lesions before and after treatment with PLX4032. We would like to exome sequence
these samples to gain a snap shot of the mechanisms of resistance that are operative.
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This dataset contains all the data available for this study on 2019-08-21.
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