Analysis of resistance to PLX4032

ABSTRACT: We have collected material from a patient who had BrafV600E mutant melanoma that was treated with PLX4032. We have germline DNA from the patient and DNA and RNA from distinct lesions before and after treatment with PLX4032. We would like to exome sequence these samples to gain a snap shot of the mechanisms of resistance that are operative.

PROVIDER: EGAS00001000415 | EGA |

REPOSITORIES: EGA