Methylation changes in OA patients with chronic exposure to cobalt and chromium

ABSTRACT: We have whole blood from a population of 70 patients, half exposed chronically to an excess of metals cobalt and chromium. The 2 groups are age, sex, and OA diagnosis matched. The 2 groups have systemic differences in bone mass and turnover, and other systemic differences. We will type the cohort of 70 individuals on the Illumina 450k methylation array and will compare between the two groups. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

PROVIDER: EGAS00001001180 | EGA |

REPOSITORIES: EGA