ENU HT 29 BRAF Triple Therapy Clones
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ABSTRACT: KRAS mutant CRC is currently in clinical trial with a combination of a MEK and Akt inhibitor. These patients will likely develop resistance to this combination. We aim to identify the mechanisms of resistance via ENU mutagenesis, with a view to identifying additional therapeutics which have the ability to overcome this resistance.
PROVIDER: EGAS00001001778 | EGA |
REPOSITORIES: EGA
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