Adenoma to Carcinoma transition in Colorectal Cancer

ABSTRACT: Although colorectal carcinoma development is well accepted as a step-wise and sequential process, it is commonly investigated using non-sequential adenoma and carcinoma samples. Here we compared molecular pathologies of the earliest carcinoma stages with those in their adenomatous precursors to unravel common and divergent genetic traits between matched neoplasms with a shared evolutionary history but different contemporary biology.

PROVIDER: EGAS00001003468 | EGA |

REPOSITORIES: EGA