Prostate Cancer mitochondrial DNA heteroplasmies and mitochondrial gene expression

ABSTRACT: Altered mitochondrial function in prostate cancer was characterized using paired malignant/non-malignant (benign) tissue samples. Mitochondrial DNA heteroplasmies (mtDNA-NGS) and mitochondria associated gene transcript levels (RNAseq-NGS) were analyzed and correlated to mitochondrial respiration (high-resolution respirometry), to each other and to the tumor stage and grade.

PROVIDER: EGAS00001004186 | EGA |

REPOSITORIES: EGA