Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia

ABSTRACT: Blast crisis (BC) predicts dismal outcomes in patients with chronic myeloid leukaemia (CML). We comprehensively investigated genetic abnormalities in 112 BC and 71 chronic phase (CP) samples obtained from 216 CML patients using exome and targeted sequencing.

PROVIDER: EGAS00001005075 | EGA |

REPOSITORIES: EGA