G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL

ABSTRACT: We describe a patient with Ph-like ALL, in which leukemic cells harbored an in-frame fusion between the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2) and the KIT proto-oncogene.

PROVIDER: EGAS00001005181 | EGA |

REPOSITORIES: EGA