ScRNAseq of human primary nasal epithelium differentiated at air-liquid interface exposed to SARS-CoV2

ABSTRACT: The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon responses are critical to outcome of SARS-CoV-2. Yet little is known about the interaction between SARS-CoV-2 and innate immunity in this tissue. Here we applied single-cell RNA sequencing and proteomics to a primary cell model of human primary nasal epithelium differentiated at air-liquid interface.

PROVIDER: EGAS00001005633 | EGA |

REPOSITORIES: EGA