Unravelling the contribution of HIF pathway and its therapeutic potential in human AML leukemia-initiating cells
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ABSTRACT: This study hypothesized that hypoxia contributes to AML-LSCs function and represents a potential therapeutic target to sensitize AML-LSCs to chemotherapy. We provide a comprehensive single-cell expression atlas of AML patient-matched diagnostic-relapsed samples from risk-stratified human AML patients.
PROVIDER: EGAS00001005980 | EGA |
REPOSITORIES: EGA
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