Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
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ABSTRACT: Single cell deep mtDNA sequencing of in vivo human female PGCs showed rare variants reaching higher heteroplasmy levels in late PGCs, consistent with the observed genetic bottleneck.
INSTRUMENT(S): Illumina MiSeq
ORGANISM(S): Homo Sapiens
SUBMITTER: University of Cambridge
PROVIDER: PRJEB56092 | EVA | 2022-09-18
REPOSITORIES: EVA
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