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Prognostic factors of stable remission after cessation of TKI therapy in chronic myeloid leukemia by whole exome sequencing

ABSTRACT: Chronic myeloid leukemia can be well controlled by targeted tyrosine kinase inhibitors (TKI). In some patients it is possible to terminate expensive and toxic long-life therapy, however about 50% of these patients relapse without treatment. In our study we found promissing new potential early prognostic markers and molecular targets for developing new drugs.

INSTRUMENT(S): Illumina

ORGANISM(S): Homo Sapiens

SUBMITTER: Federal State Budgetary Institution «Research Centre For Medical Genetics», Moscow, Russia

PROVIDER: PRJEB9858 | EVA | 2015-07-12

REPOSITORIES: EVA

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