Models

Dataset Information

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E.coli Core Model with Beta Oxidation Cycle.


ABSTRACT: E.coli Core Model with Beta Oxidation Cycle.

SUBMITTER: Natalie Stanford 

PROVIDER: 160 | FAIRDOMHub | 2016-06-02

REPOSITORIES: FAIRDOMHub

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Publications

RobOKoD: microbial strain design for (over)production of target compounds.

Stanford Natalie J NJ   Millard Pierre P   Swainston Neil N  

Frontiers in cell and developmental biology 20150324


Sustainable production of target compounds such as biofuels and high-value chemicals for pharmaceutical, agrochemical, and chemical industries is becoming an increasing priority given their current dependency upon diminishing petrochemical resources. Designing these strains is difficult, with current methods focusing primarily on knocking-out genes, dismissing other vital steps of strain design including the overexpression and dampening of genes. The design predictions from current methods also  ...[more]

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