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Detailed kinetic model of yeast glycolytic oscillation - VII

ABSTRACT: Detailed kinetic model of yeast glycolytic oscillation - VII

SUBMITTER: Franco du Preez

PROVIDER: 80 | FAIRDOMHub | 2012-07-23

REPOSITORIES: FAIRDOMHub

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From steady-state to synchronized yeast glycolytic oscillations II: model validation.

du Preez Franco B FB van Niekerk David D DD Snoep Jacky L JL

The FEBS journal 20120705 16

<h4>Unlabelled</h4>In an accompanying paper [du Preez et al., (2012) FEBS J279, 2810-2822], we adapt an existing kinetic model for steady-state yeast glycolysis to simulate limit-cycle oscillations. Here we validate the model by testing its capacity to simulate a wide range of experiments on dynamics of yeast glycolysis. In addition to its description of the oscillations of glycolytic intermediates in intact cells and the rapid synchronization observed when mixing out-of-phase oscillatory cell p ...[more]

PMID: 22686585

Publication: 1/2

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