Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

OTHER RELATED OMICS DATASETS IN: PRJNA390636PXD004807PRJNA390631PRJNA390635

ORGANISM(S): Homo sapiens

PROVIDER: GSE100076 | GEO | 2018/01/12

SECONDARY ACCESSION(S): PRJNA390631

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq]

Project description:We report the first discovery of naturally occurring ESR1Y537C and ESR1Y537S mutations in MCF7 and SUM44 ESR1-positive cell-lines after acquisition of resistance to long-term-estrogen-deprivation (LTED) and subsequent resistance to fulvestrant (ICIR).

2018-01-12 | GSE100075 | GEO

Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [ChIP-Seq]

Project description:We report the first discovery of naturally occurring ESR1Y537C and ESR1Y537S mutations in MCF7 and MCF7 ESR1-positive cell-lines after acquisition of resistance to long-term-estrogen-deprivation (LTED) and subsequent resistance to fulvestrant (ICIR).

2018-01-12 | GSE100074 | GEO

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.

Project description: Not available

| S-EPMC5709387 | biostudies-literature

Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines

Project description:Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines

| PRJNA390631 | ENA

Analyzing effects of naturally occurring missense mutations.

Project description: Not available

| S-EPMC3346971 | biostudies-literature

Naturally occurring mutations in the canine CFTR gene.

Project description: Not available

| S-EPMC2929888 | biostudies-literature

Biophysical characterization of naturally occurring titin M10 mutations.

Project description: Not available

| S-EPMC4456108 | biostudies-literature

Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.

Project description: Not available