Microbiome characterization using transfer RNA sequencing

ABSTRACT: Here we report a direct tRNA sequencing protocol and software to simultaneously examine the composition and biological activity of naturally occurring microbial communities. Our analysis of mouse gut microbiome with tRNA-seq and 16S ribosomal RNA gene amplicons revealed comparable microbial community structures, and additional physiological insights into the microbiome through tRNA abundance and modifications.

ORGANISM(S): Escherichia coli Barnesiella viscericola Staphylococcus aureus Bacillus subtilis mouse gut metagenome

PROVIDER: GSE100263 | GEO | 2018/11/09

REPOSITORIES: GEO