Transcriptomics,Genomics

Dataset Information

25

Expression data from MDS patients with der(1;7)(q10;p10)


ABSTRACT: Gene expression profiling was significantly different between der(1;7)(q10;p10) and -7/7q- patients by cluster analysis. There were total 1628 dysregulated genes in both der(1;7)(q10;p10) and -7/del(7q) cohorts. Overall design: In order to identify the possible candidate genes implicated in the initiation or maintenance of MDS patients with der(1;7)(q10;p10), we performed the gene expression array (Affymetrix Human Genome U133 Plus 2.0 Array, USA) in 7 der(1;7)(q10;p10)(A1,A2,A3,A5,A6,A11,A12) and 6 -7/7q- samples(B3,B4,B5,B6,B8,B9).

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

SUBMITTER: Tongtong Zhang  

PROVIDER: GSE100340 | GEO | 2017-09-22

SECONDARY ACCESSION(S): PRJNA391405

REPOSITORIES: GEO

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Publications

High frequency of RUNX1 mutation in myelodysplastic syndrome patients with whole-arm translocation of der(1;7)(q10;p10).

Zhang T T   Xu Y Y   Pan J J   Li H H   Wang Q Q   Wen L L   Wu D D   Sun A A   Chen S S  

Leukemia 20170719 10


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