Genomics

Dataset Information

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Caffeine-regulated transcripts in mouse hearts are p27-dependent


ABSTRACT: Overall question: How does caffeine administration for 10 days with the drinking water change the transcriptome of the heart? Are these changes dependent on the protein p27? Results: 242 of the 245 transcripts differentially regulated after caffeine administration in wildtype animals are p27 dependent, since they are not changed in p27-deficient littermates. Among the most highly enriched gene ontology (GO) categories for biological processes are GO-terms describing pathways, which take place in the mitochondria.

ORGANISM(S): Mus musculus

PROVIDER: GSE100489 | GEO | 2017/11/30

SECONDARY ACCESSION(S): PRJNA391941

REPOSITORIES: GEO

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