Transcriptomics

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Large-scale tethering of RNA binding proteins discovers alternative splicing regulators [microarray]


ABSTRACT: To elucidate the role of large sets of RBPs, we developed a comprehensive and diverse plasmid resource3 of 765 RBPs fused to the MS2 bacteriophage coat protein. When systematically tethered to an intronic 4 MS2 hairpin downstream of an alternative exon, we identified 55 RBPs that significantly induced exon 5 retention.

ORGANISM(S): Homo sapiens

PROVIDER: GSE100600 | GEO | 2025/04/27

REPOSITORIES: GEO

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