RNA-Seq analysis of breast cancer cells after shikonin treatment

ABSTRACT: We performed RNA-seq analysis using differnt breast cancer cell lines (MCF-7, SK-BR-3 and MDA-MB-231) after shikonin treatment. We reported that shikonin enhances the expression of DUSP-1 and DUSP-2. Shikonin induces apoptosis and decreases the phosphorylation of JNK1/2 through activationg DUSP-1 and DUSP2.

ORGANISM(S): Homo sapiens

PROVIDER: GSE100687 | GEO | 2018/02/13

REPOSITORIES: GEO