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Mechanisms of Cancer Resistance to Immunogenic Cytotoxicity

ABSTRACT: The majority of cancer patients do not respond to immunotherapy. In order to systematically discover pathways promoting cancer cell resistance to effector immune cells, we generated immunity-resistant Head and Neck Squamous Cell Carcinoma cell lines. We utilized RNA-Seq to determine what are the genes and pathways that are significantly altered when cancer cells become resistant to effectors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE100828 | GEO | 2018/12/25

REPOSITORIES: GEO

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