Single cell transcriptomics reveal an essential role for Hippo signaling in cell state transitions during cardiac fibroblast development

ABSTRACT: We use single cell RNA-sequencing (Drop-seq) to profile cardiac cells (excluded atria) from control (Wt1 CreERT2/+; Rosa26mTmG/+) and epicardial-deficient Lats1/2 kinase embryonic hearts (Wt1 CreERT2/+; Lats1/2 F/F; Rosa26mTmG/+) at E13.5 and E14.5.  Each experimental group includes cells sampled from four embryonic hearts.

ORGANISM(S): Mus musculus

PROVIDER: GSE100861 | GEO | 2018/04/23

REPOSITORIES: GEO