Sensors, Pathways and Transcription factors regulating IR-induced inflammatory transcriptional output [RNA-seq data set 1]

ABSTRACT: Bone marrow-derived macrophages derived from C57Bl/6, Myd88-/- and Trif-/-, Ifnar-/-, Atm-/-, Sting-/-, Scid, Irf3-/-, Irf1-/-, p53-/-, Nrf2-/-mice were irradiated with 6Gray ioninzing radiation; C57Bl/6 macrophages were Irradiated in the presence of MAPK inhibitors or Reactive Oxygen Species Scavenger (N-Acetyl Cysteine), Two biological replicates were generated for each time point. RNA samples were collected at 0 (unirradiated), 0.5, 1, 2, 6, and 24h post irradiation except where ever mentioned.

ORGANISM(S): Mus musculus

PROVIDER: GSE100961 | GEO | 2017/10/01

SECONDARY ACCESSION(S): PRJNA393535

REPOSITORIES: GEO