Transcriptomics

Dataset Information

0

RNA-seq data of intestinal epithelial cells and lamina propria dendritic cells


ABSTRACT: We report that Klebsiella pneumoniae promote Th1 cell induction in colon. To examine the influence of Klebsiella on colonic epithelial cells (ECs) and lamina propria CD11c+ dendritic cells (DCs), we performed RNA seq on them. Germ free mice were orally inoculated with Kp-2H7 or BAA-2552 and total RNA was isolated from colonic ECs and DCs 1 week after inoculation. Furthermore, we examined the involvement of TLRs in induction of Th1 cells using Myd88 KO, Trif KO, Myd88/Trif DKO mice. These deficient germ free mice were orally inoculated with Kp-2H7 and total RNA was isolated from colonic ECs 3 weeks after inoculation.

ORGANISM(S): Mus musculus

PROVIDER: GSE101678 | GEO | 2017/10/20

SECONDARY ACCESSION(S): PRJNA395175

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| EGAD00001004465 | EGA
2015-09-24 | GSE71734 | GEO
2023-08-31 | GSE235114 | GEO
2015-09-24 | E-GEOD-71734 | biostudies-arrayexpress
2018-03-10 | GSE79614 | GEO
2018-03-10 | GSE79581 | GEO
2018-03-10 | GSE79062 | GEO
2008-11-22 | E-GEOD-13147 | biostudies-arrayexpress
2012-12-31 | E-GEOD-35927 | biostudies-arrayexpress
2018-03-10 | GSE79591 | GEO