Rlim-independent XCI in female embryonic stem cells in vitro

ABSTRACT: The transcriptomes of differentiated and undifferentiated E14 (male), Pgk12.1 (female; WT) and Pgk12.1 with a KO of Rlim (RlimKO) were elucidated and examined for differences in X chromosome inactivation. No significant differences between wt and RlimKO with respect to Xist expression and global X-silencing was detected. Results confirm that Rlim is not required for XCI in female ESCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE101838 | GEO | 2017/12/26

SECONDARY ACCESSION(S): PRJNA395658

REPOSITORIES: GEO