Systems Biology of Influenza A (H5N1) Virus Monovalent Vaccine with and without AS03 adjuvant

ABSTRACT: H5N1 influenza vaccine is known to induce diminished antibody responses in vaccine recipients without the use of adjuvant. We hypothesize that this is due to intrinsic defects in innate responses that could explain the poor immunogenicity of the vaccine. These innate responses may be improved with use of an adjuvant, e.g., AS03.

ORGANISM(S): Homo sapiens

PROVIDER: GSE102012 | GEO | 2021/06/29

REPOSITORIES: GEO