Genomics

Dataset Information

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The role of TEFM in mitochondrial gene expression [TruSeq]


ABSTRACT: We investigated the role of TEFM in vivo by creating heart- and skeletal-muscle specific knockout of this gene. We identified that TEFM is required for the processivity of POLRMT and its loss leads to significantly decreased mitochondrial transcription. Overall design: Total RNA from isolated heart mitochondria from four control mice (L/L) and four Tefm knockout mice (L/L, cre), was sequenced and analysed for differential expression.

INSTRUMENT(S): Illumina MiSeq (Mus musculus)

ORGANISM(S): Mus musculus  

SUBMITTER: Stefan J Siira 

PROVIDER: GSE102254 | GEO | 2019-04-01

REPOSITORIES: GEO

Dataset's files

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GSE102254_RAW.tar Raw
GSE102254_TruSeq.DESeq2_results.txt.gz Txt
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