The role of TEFM in mitochondrial gene expression [TruSeq]

ABSTRACT: We investigated the role of TEFM in vivo by creating heart- and skeletal-muscle specific knockout of this gene. We identified that TEFM is required for the processivity of POLRMT and its loss leads to significantly decreased mitochondrial transcription.

ORGANISM(S): Mus musculus

PROVIDER: GSE102254 | GEO | 2019/04/01

REPOSITORIES: GEO