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Change in circulating miRNA at two weeks after anti-TNF therapy predicts response at 14 weeks: a pilot study

ABSTRACT: Circulating microRNA were collected from RA patients before and 2, 4, and 14 weeks after anti-TNF (Golimumab) treatment. Changes in expression from baseline to 2 weeks are predictive of response, whereas changes to 4 and 14 weeks are not. This study suggests the importance of collecting early biomarker samples post-treatment to evaluate efficacy and guide therapy.

ORGANISM(S): Homo sapiens

PROVIDER: GSE102263 | GEO | 2020/11/22

REPOSITORIES: GEO

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