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Expression data from WT and AIMp1KO mouse bone marrow-derived dendritic cells

ABSTRACT: Dendritic cells are critical regulators of adaptive immune responses which can process and present antigens to effector cells. As a structural component of multi-enzyme aminoacyl tRNA synthetase complex, AIMp1 (p43) is identified to promote type 1 T-cell responses by DCs and play important roles in both antitumor and antiviral immunity. We use high-throughput microarray analysis to compare the gene expression profiles of WT vs. AIMp1KO bone marrow-derived DCs (BMDC) to study the mechanism by which DC-expressed AIMp1 promote type 1 T-cell immune responses.

ORGANISM(S): Mus musculus

PROVIDER: GSE102282 | GEO | 2017/11/30

SECONDARY ACCESSION(S): PRJNA397213

REPOSITORIES: GEO

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