Expression data for the molecular signature of TF1a acute myeloid leukaemia cell line
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ABSTRACT: TF1a AML cell line was selected for in vitro modelling of dormancy in AML. TF1-a were subjected to AML-niche-mimicking in vitro conditioning by culture with TGFB1 and the mTOR inhibitor rapamycin. Also TF1a cells were in vitro cultured with prolonged sublethal doses of Etoposide. The molecular signature of untreated, dormancy induced and genotoxicity-surviving TF1a cells were investigated using global human genome GEP to identify drivers of dormancy in different conditioning scenarios in comparison to untreated counterparts.
ORGANISM(S): Homo sapiens
PROVIDER: GSE102483 | GEO | 2018/02/27
REPOSITORIES: GEO
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