Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Enhancer analysis of rat cardiac myocytes and fibroblasts reveals a collaborative control by transcription factor families

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE102532 | GEO | 2018/02/06

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Enhancer analysis of rat cardiac myocytes and fibroblasts reveals a collaborative control by transcription factor families [ChIP-Seq]

Project description:We used a differential open chromatin approach, coupled with active enhancer mark ,transcriptomic and computational TFs binding analysis to map cell-type-specific active enhancers in cardiac fibroblasts and cardiomyocytes, and outline the TFs that control them. We identified Tead, Sox9, Smad, Tcf, Meis, Rbpj, and Runx1 as the main cardiac fibroblasts TF groups. Our analysis shows that in cardiomyocytes and cardiac fibroblasts, distal enhancers, containing concentrated combinatorial clusters of multiple tissue expressed TFs recognition motifs, are combinatorically clustered around tissue specific genes.

2018-02-06 | GSE102530 | GEO

Enhancer analysis of rat cardiac myocytes and fibroblasts reveals a collaborative control by transcription factor families [ATAC-Seq]

2018-02-06 | GSE102529 | GEO

Enhancer analysis of rat cardiac myocytes and fibroblasts reveals a collaborative control by transcription factor families [RNA-Seq]

2018-02-06 | GSE102531 | GEO

Enhancer analysis of rat cardiac myocytes and fibroblasts reveals a collaborative control by transcription factor families

Project description:Enhancer analysis of rat cardiac myocytes and fibroblasts reveals a collaborative control by transcription factor families

| PRJNA397976 | ENA

siRNA knockdown of neonatal rat cardiac myocytes and fibroblasts

Project description:Primary neonatal rat cardiac myocytes or fibroblasts were isolated and subjected to siRNA mediated Yap knockdown

2018-10-30 | GSE112464 | GEO