Genomics

Dataset Information

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IRF4 haploinsufficiency in a family with Whipple’s disease


ABSTRACT: Whipple's disease (WD) affects only a very small minority of individuals infected by Tropheryma whipplei (Tw). Asymptomatic and chronic carriage of the causative organism is less rare and therefore, the pathogenesis of WD is poorly understood. Here we studied transcriptome responses in peripheral blood mononuclear cells (PBMCs) that were obtained from members of a large multiplex French kindred including otherwise healthy WD patients, healthy chronic carriers of Tw and other unrealted control subjects.

ORGANISM(S): Homo sapiens

PROVIDER: GSE102862 | GEO | 2017/10/30

SECONDARY ACCESSION(S): PRJNA415625

REPOSITORIES: GEO

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