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ATAC-seq analyses during spermatogenesis

ABSTRACT: To determine the dynamics of open chromatin at a genomic resolution during spermatogenesis, we performed ATAC-seq and detected genomic regions of accessible chromatin by Tn5 transposase during spermatogenesis. We analyzed four representative stages of spermatogenesis: Thy1+ undifferentiated spermatogonia, which contains spermatogonial stem cells and progenitor cells; c-Kit+ differentiating spermatogonia from P7 testes; purified pachytene spermatocytes (PS) undergoing meiosis; and postmeiotic round spermatids (RS) from adult testes

ORGANISM(S): Mus musculus

PROVIDER: GSE102954 | GEO | 2017/10/18

SECONDARY ACCESSION(S): PRJNA399533

REPOSITORIES: GEO

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