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Preconception Urinary Phthalate Concentrations and Sperm DNA Methylation Profiles among Men Undergoing IVF Treatment: A Cross-Sectional Study

ABSTRACT: To answer the question of whether preconception phthalate and phthalate replacements associated with sperm differentially methylated regions (DMRs) among men undergoing in-vitro fertilization, genome-wide DNA-methylation profiles of 48 human sperm samples were generated by bisulfite-based Illumina 450K BeadChip arrays. The sperm DNA methylation is then correlated with urinary phthalate metabolite concentrations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE102970 | GEO | 2017/10/01

SECONDARY ACCESSION(S): PRJNA399706

REPOSITORIES: GEO

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