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Microarray whole transcriptome profiling of LPS (Escherichia coli O111:B4) treated BV-2 Cells

ABSTRACT: A common in vitro model for evaluating anti-inflammatory agents is use of lipopolysaccharide (LPS) , a cell wall endotoxic component from gram negative bacteria which evokes a deadly cytokine storm associated with septicemia, septic shock and multi organ failure. In this study , we investigate whole transcriptome changes occurring at 24 hours of incubation with LPS (1ug/ml) in BV2 murine microglia cells. Microarrays were acquired for mRNAs and long intergenic non-coding RNA transcripts using the GeneChip™ MOGENE 2.1ST ARRAY Arrays by Affymetrix Inc.

ORGANISM(S): Mus musculus

PROVIDER: GSE103156 | GEO | 2017/08/29

SECONDARY ACCESSION(S): PRJNA400370

REPOSITORIES: GEO

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