High-throughput deep sequence of zebrafish wild-type and ezh2 mutant embryos

ABSTRACT: To determine the molecular basis for the reduced blood cells in circulation in ezh2 mutant zebrafish, we performed high-throughput sequencing at 28 hpf. Results revealed 893 up-regulated genes and 425 down-regulated genes in the ezh2 mutant zebrafish compared with wild-type zebrafish. We found that some hematopoietic genes are down-regulated in ezh2 mutant zebrafish, which was reconfirmed with qRT-PCR.

ORGANISM(S): Danio rerio

PROVIDER: GSE103913 | GEO | 2018/02/06

REPOSITORIES: GEO