IMM_IL-17RC_KO mice_exp1

ABSTRACT: This study identifies a novel mechanism linking IL-17A with colon tissue repair and tumor development. Abrogation of IL-17A signaling mice attenuated tissue repair of DSS-induced damage in colon epithelium and markedly reduced tumor development in AOM/DSS model of colitis-associated cancer. The goal of these studies is to identify genes associated with IL-17RC deficiency during AOM-DSS induced tumorigenesis

ORGANISM(S): Mus musculus

PROVIDER: GSE104122 | GEO | 2017/09/25

SECONDARY ACCESSION(S): PRJNA411836

REPOSITORIES: GEO