MicroRNA expression profiles predict the response to PegIFNα-2a treatment of Chronic Hepatitis B

ABSTRACT: The differential expression profiles of PBMCs microRNA pretreatment between the HBsAg loss group and the non-HBsAg loss group were constructed by using the miRCURYTM LNA Array (v.19.0)(Exiqon), the results were validated by qRT-PCR,all the expresison levels of selected microRNAs were consistent with the microarray results. The receiver operating characteristic curve was performed to estimate the predictive value of the selected miRNAs,indicated that microRNAs may be potential predictive biomarkers for PegIFN response.

ORGANISM(S): Mus musculus Rattus norvegicus Homo sapiens

PROVIDER: GSE104126 | GEO | 2018/03/31

REPOSITORIES: GEO