Expression data from SOX9 overexpressing EndoC-ßH1 cells

ABSTRACT: Human ß cell dedifferentiation as a potent mechanism of diabetes is gaining prominence. Several data suggest an upregulation of the transcription factor SOX9, a progenitor and duct cell marker during ß cell dedifferentiation. However, its targets in such cells need more understanding. Here, we overexpressed SOX9 and a constitutively active mutant (VP16-SOX9∆TAD) in Human pancreatic beta EndoC-ßH1 cells in order to understand its targets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE104195 | GEO | 2018/01/31

REPOSITORIES: GEO