Fibrinogen activates BMP signaling in oligodendrocyte progenitor cells (OPCs) and inhibits remyelination after vascular damage [Rat_OPC_48h_Fibrinogen]

ABSTRACT: Determination of the mechanism by which fibrinogen, a central blood coagulation protein, regulates OPC functions and remyelination in the CNS. We used microarrays to determine the genes involved in OPC responses to fibrinogen, which is deposited in the CNS after blood-brain barrier disruption.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE104449 | GEO | 2017/11/02

SECONDARY ACCESSION(S): PRJNA412656

REPOSITORIES: GEO