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Cellular metabolism constraints innate immune responses in early human ontogeny

ABSTRACT: We compared LPS responses (5h) between preterm (<30 weeks) neonatal, term neonatal and adult human monocytes at the genome-wide transcriptome level.

ORGANISM(S): Homo sapiens

PROVIDER: GSE104510 | GEO | 2018/09/22

REPOSITORIES: GEO

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Cellular metabolism constrains innate immune responses in early human ontogeny.

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Cellular metabolism constraints innate immune responses in early human ontogeny

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Project description:We sought to determine the impact of chorioamnionitis exposure on term neonatal monocyte transcription. RNA-seq was performed on term healthy and chorioamnionitis-exposed umbilical cord blood purified CD14+ monocytes under unstimulated and LPS stimulated conditions.

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