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Interleukin-1β effect on primary mouse articular chondrocytes

ABSTRACT: Gene expression profiling of primary mouse articular chondrocyte treated with interleukin-1β. In this study, we have attempted to explore the effects of interleukin-1β on mouse transcriptome and have identified numerous genes which are involved in osteoarthritis pathogenesis.

ORGANISM(S): Mus musculus

PROVIDER: GSE104793 | GEO | 2017/10/10

SECONDARY ACCESSION(S): PRJNA413832

REPOSITORIES: GEO

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Interleukin-1β effect on primary mouse articular chondrocytes

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Expression in equine cartilage stimulated with IL-1β in vitro

Project description:The objective was to study the time-course effects of interleukin-1β (IL-1β) on equine articular cartilage, with the aim to identify genes of relevance for cartilage pathology in osteoarthritis. Changes in gene expression related to inflammation, extracellular matrix, and phenotypic alterations was studied.

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