Transcriptomics

Dataset Information

23

Differential gene expression from azithromycin and SMM treated human airway epithelium


ABSTRACT: Microarrays were used to evaluate the effects of azithromycin and an inflammatory stimulus (SMM) on human airway epithelium. Effects of azithromycin treatment were evaluated at 6, 24 and 48 hours. Effects of SMM were evaluated at 6 and 24 hours. In addition, pretreatment with azithromycin was used to evaluate the modulatory effects on SMM-induced inflammation. SMM=supernatant from microcorpulent material from human cystic fibrosis airways. Keywords: timecourse, treatment comparisons. Overall design: 10 treatments total, 3-4 samples (patient codes = replicates) per treatment.

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: Wanda K. O'Neal  

PROVIDER: GSE10592 | GEO | 2009-05-19

SECONDARY ACCESSION(S): PRJNA107747

REPOSITORIES: GEO

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