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Microarray Analysis of Toxicogenomic Effects of Ortho-Phenylphenol on Staphylococcus aureus

ABSTRACT: In the present study, we employed Affymetrix Staphylococcus aureus GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Staphylococcus aureus to Ortho-Phenylphenol, which involved initial growth inhibition and metabolism. Keywords: Time course

ORGANISM(S): Staphylococcus aureus

PROVIDER: GSE10605 | GEO | 2008/04/01

SECONDARY ACCESSION(S): PRJNA107773

REPOSITORIES: GEO

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Microarray Analysis of Toxicogenomic Effects of Ortho-Phenylphenol on Staphylococcus aureus

Project description:In the present study, we employed Affymetrix Staphylococcus aureus GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Staphylococcus aureus to Ortho-Phenylphenol, which involved initial growth inhibition and metabolism. Keywords: Time course We conducted five independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of Ortho-Phenylphenol. We calculated fold change as the ratio between the signal averages of five untreated (control) and five ortho-phenylphenol-treated (experimental) cultures for 0, 20 and 60 min exposures.

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